Cardiogenic Shock: The Main Cause of Mortality in Acute Aluminum Phosphide Poisoning
نویسندگان
چکیده
Indian Journal of Critical Care Medicine ¦ Volume 21 ¦ Issue 4 ¦ April 2017 246 adhesion molecule-1, thrombospondin, and histidine-rich protein causing microcirculatory obstruction.[3] Disseminated intravascular coagulation is also a contributing factor in malaria-related SPG and is rarely associated with significant bleeding.[4] Management of SPG in malaria is supportive. There is no specific treatment for SPG per se and routine use of antiplatelets or anticoagulants is not indicated. The mortality rate of SPG is almost 35% and 70%–90% patients might need amputation after line of demarcation develops.[5]
منابع مشابه
Successful Treatment of Severe Metabolic Acidosis Due to Acute Aluminum Phosphide Poisoning With Peritoneal Dialysis: a Report of 2 Cases.
Aluminum phosphide poisoning is common in our region. It can cause severe metabolic acidosis and persistent hypotension, which lead to cardiogenic shock and subsequently mortality. Oliguric or anuric acute kidney injury is seen in almost all patients with aluminum phosphide poisoning. Renal replacement therapies are recommended in these patients to improve metabolic acidosis and increase the ra...
متن کاملFrequency of Cardiac Arrhythmias in Patients with Aluminum Phosphide Poisoning
Background: Cardiac failure is the major lethal consequence of aluminum phosphide (AlP) poisoning. This study was designed to determine the frequency of cardiac arrhythmias in patients with AlP poisoning. Methods: In this prospective cross-sectional study, patients with definitive history of AlP poisoning treated at emergency department of Allied Hospital Faisalabad, Faisalabad, Pakistan, from ...
متن کاملSuccessful Treatment of Aluminium Phosphide Poisoning: A Case Report
Aluminium phosphide (AlP) is used to kill rodents in grain storage. It produces phosphine gas which is toxic for mitochondria. The exact mechanism of action is unclear, but phosphine is thought to produce toxicity by blocking cytochrome-c oxidase, which inhibits oxidative phosphorylation and result in cell death. This poisoning has a high mortality, and survival is unlikely if more than 1.5 g i...
متن کاملUsing Intra-Aortic Balloon Pump for Management of Cardiogenic Shock Following Aluminum Phosphide Poisoning; Report of 3 Cases
Introduction Aluminium phosphide (Alp) poisoning mortality rate has been reported as high as 70-100%, and refractory hypotension and cardiogenic shock are the two most common presentations leading to death. Due to lack of specific antidote, all treatments are focused on supportive care and recently, intra-aortic balloon pump (IABP) has been suggested to treat cardiogenic shock resulting from to...
متن کاملPolyserositis: An Unusual Complication of Aluminum Phosphide Poisoning
Background: Aluminum phosphide is the common cause of poisoning in adults in India, with a very high case fatality ratio. We studied five patients of aluminum phosphide poisoning with polyserositis. Methods: We enrolled all patients with aluminum phosphide poisoning presenting to emergency medical department, at a tertiary care hospital in northwestern India from January to July 2006. These p...
متن کامل